Laboratory Systems Strengthening
Since 2007, Baylor-Uganda, with funding from CDC and USAID, has been supporting the Ministry of Health to build a laboratory network with the capacity to provide diagnostic and surveillance services. Baylor Uganda uses the Strengthening Laboratory Management Towards Accreditation (SLMTA) approach to train labs to implement the Laboratory Quality Management System (LQMS) and attain international accreditation status. Baylor-Uganda also supports Laboratory infrastructure and equipment procurement, Laboratory equipment management through subgrants to two regional laboratory equipment workshops, supply chain management, Biosafety and Biosecurity and a robust specimen referral and transportation system. The Laboratory capacity-building program is done through training, mentorships and quality assurance in collaboration with Uganda MOH’s National Health Laboratory System (UNHLS). Through this capacity, the laboratory network is able to deliver quality results to inform clinical decisions, early detection and response to disease outbreaks.
ANTIMICROBIAL RESISTANCE (AMR) PREVENTION AND CONTROL
FIELD EPIDEMIOLOGY TRAINING PROGRAM (FETP)
- Investigation of possible preventable causes of COVID-19 deaths in the Kampala Metropolitan Area, Uganda, 2020–2021.
- Community Dialogue Meetings among District Leaders Improved Their Willingness to Receive COVID-19 Vaccines in Western Uganda, May 2021. https://uniph.go.ug/district-leader-community-dialogue-meetings-improved-willingness-to-receive-covid-19-vaccines-in-western-uganda-may-2021-a-pre-post-study/
- High blood pressure and associated factors among HIV-infected persons aged 13 to 25 years selected health facilities in Rwenzori region, western Uganda, September–October 2021.
- Birth outcomes among HIV-positive women in Rwenzori region, Western Uganda, 2021.
- Individual and household risk factors for COVID-19 infection among household members of COVID-19 patients in Home based care in Western Uganda, 2020.
- Factors associated with retention in care among HIV-exposed infants in Rwenzori region, Western Uganda.
- Cascade of NCD care in HIV clinics in Western-Uganda
- Effects of COVID-19 on ART services utilisation among people living with HIV and AIDS in the Rwenzori Region, Mid-Western Uganda, 2020-2021
COVID-19 VACCINE TRIALS
Baylor-Uganda is implementing two clinical trials to test the efficacy of COVID-19 vaccines:
CoVPN 3008 (Ubuntu): Multi-Center, Randomized, Efficacy Study of COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern:
The study is designed to help inform which vaccine regimen, likely in combination with enhanced HIV care, could serve as a public health model for an effective and cost-efficient approach to preventing SARS-CoV-2 disease, prolonged viral shedding, and the emergence of VOCs within this population. The study will also evaluate whether immune responses postvaccination can be correlated to these clinically important outcomes. The study will enroll 15,600 adults from many clinics in Eastern and Southern Africa. All participants in the study will get the study vaccine.
VAT 00008(COVPN 3005): A parallel-group, Phase III, multi-stage, modified double-blind, multi-armed study to assess the efficacy, safety, and immunogenicity of two SARS-CoV-2 Adjuvanted Recombinant Protein Vaccines (monovalent and bivalent) for prevention against COVID-19 in adults 18 years of age and older