As the world strives to end morbidity and mortality due to HIV/AIDS, Baylor-Uganda complements these global efforts through implementing data-driven approaches under all its projects. Guided by the national treatment guidelines for comprehensive HIV care, we are currently supporting over 300 health facilities across 30 districts in Uganda to improve the quality of life among people living with HIV/AIDS (PLHIV). Our implementation approach is majorly through strengthening health systems while underscoring effectiveness & efficiency, governance and leadership, local partnerships as well as sustainability of all our interventions. We currently run a centre of excellence HIV clinic in Mulago hospital complex as well as support through district led programming 3 HIV care and treatment projects; ACE-FORT in mid-western Uganda, and ACE-Bunyoro in western Uganda both funded through Centres for Disease Control and Prevention (CDC) Uganda and the USAID Local Partner Health Services – Eastern Region (USAID LPHS-E). Key areas of focus under HIV care and Treatment include; HIV case identification and anti-retroviral therapy to all, TB case finding and treatment, Cervical cancer screening and treatment/management as well as identification and management of advanced HIV disease. All treatment indicators are driven by the need to reached the third 95% of clients on ART being virally suppressed as well as ensuring all PLHIV with opportunistic infections including TB, Cryptococcal meningitis, cervical cancer among others are well managed.