The Global Health Security Program focuses on Improving Health Security and Building International Health Regulations core capacities in the Republic of Uganda. The Directorate aims to strengthen country-level capacity to prevent, detect and respond to public health threats of national and international concern.
Key targets in strategic plan: The Directorate contributes to Strategic Objective 2 in the strategic plan “Strengthen prevention, detection and response to public health threats/emergencies”
Structure of the directorate: The Director, Global Health Security Oversees the directorate with support from a Program Manager , M&E Manger and Project Coordinators
The CDC funded Global Health Security Project (2020-2024); a 5-year grant seeking to strengthen further, establish and sustain Uganda’s capacity to implement core GHSA priorities and comply with IHR (2005). Project strategic objectives are to:
The project currently operates at the national level, in the Rwenzori (9 districts, one city) and Bunyoro (8 districts, 1 city) regions, and other regions as the need arises, especially for emergency response work.
The GIZ funded KCCA COVID-19 Project (2022-2023); a 1-year grant seeking to Strengthen linkages between COVID-19 testing, surveillance and Home-based care to support the containment of COVID-19 in Kampala. Project strategic objectives are to:
The project currently operates in five divisions (Central, Nakawa, Makindye, Rubaga, and Kawempe).
The WHO Funded COVID-19 Contact Tracing and Follow up Project (2021); a short-term grant that supported the Ministry of Health (MOH) to strengthen reporting, contact tracing and follow up in selected regions. Project strategic objectives were to:
The project was implemented in across 63 districts in six health regions of Jinja, Masaka, Mbale, Moroto, Mubende and Soroti.
Since 2007, Baylor-Uganda, with funding from CDC and USAID, has been supporting the Ministry of Health to build a laboratory network with the capacity to provide diagnostic and surveillance services. Baylor Uganda uses the Strengthening Laboratory Management Towards Accreditation (SLMTA) approach to train labs to implement the Laboratory Quality Management System (LQMS) and attain international accreditation status. Baylor-Uganda also supports Laboratory infrastructure and equipment procurement, Laboratory equipment management through subgrants to two regional laboratory equipment workshops, supply chain management, Biosafety and Biosecurity and a robust specimen referral and transportation system. The Laboratory capacity-building program is done through training, mentorships and quality assurance in collaboration with Uganda MOH’s National Health Laboratory System (UNHLS). Through this capacity, the laboratory network is able to deliver quality results to inform clinical decisions, early detection and response to disease outbreaks.
Baylor-Uganda is implementing two clinical trials to test the efficacy of COVID-19 vaccines:
CoVPN 3008 (Ubuntu): Multi-Center, Randomized, Efficacy Study of COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern:
The study is designed to help inform which vaccine regimen, likely in combination with enhanced HIV care, could serve as a public health model for an effective and cost-efficient approach to preventing SARS-CoV-2 disease, prolonged viral shedding, and the emergence of VOCs within this population. The study will also evaluate whether immune responses postvaccination can be correlated to these clinically important outcomes. The study will enroll 15,600 adults from many clinics in Eastern and Southern Africa. All participants in the study will get the study vaccine.
VAT 00008(COVPN 3005): A parallel-group, Phase III, multi-stage, modified double-blind, multi-armed study to assess the efficacy, safety, and immunogenicity of two SARS-CoV-2 Adjuvanted Recombinant Protein Vaccines (monovalent and bivalent) for prevention against COVID-19 in adults 18 years of age and older
The Ministry of Health (MoH) started to roll out COVID-19 vaccination in May 2021. Since then, Baylor-Uganda has supported the Ministry of Health (MoH) through the Uganda National Expanded Program on Immunization (UNEPI) to implement routine/targeted COVID-19 vaccination and Accelerated Mass Vaccination Campaigns (AMVC) at the national and subnational level (17 districts and two cities in Bunyoro and Rwenzori regions). Our support includes capacity building for healthcare workers (HCWs) and community mobilizers, microplanning and coordination, supportive supervision and mentorship, vaccine supply chain management, data management, Advocacy, risk communication and community engagement. As of August 2022, 88% (2,625,739) and 61% (1,816,732) of the target population people from Rwenzori and Hoima regions had received the first dose and were fully vaccinated for COVID-19 respectively.